SrasV1, Main, Exploration, bibRecord, 004440

Inactivation of SARS coronavirus by means of povidone-lodine, physical conditions and chemical reagents

Identifieur interne : 004440 ( Main/Exploration ); précédent : 004439; suivant : 004441

Inactivation of SARS coronavirus by means of povidone-lodine, physical conditions and chemical reagents

Auteurs : Hiroaki Kariwa [Japon] ; Nobuhiro Fujii [Japon] ; Ikuo Takashima [Japon]

Source :

Dermatology : (Basel) [ 1018-8665 ] ; 2006.

RBID : Pascal:06-0170112

Descripteurs français

KwdFr :
- Acétone (pharmacologie), Animaux, Anti-infectieux locaux (pharmacologie), Antiviraux (pharmacologie), Cellules Vero, Formaldéhyde (pharmacologie), Glutaraldéhyde (pharmacologie), Inactivation virale, Indicateurs et réactifs (pharmacologie), Méthanol (pharmacologie), Povidone iodée (pharmacologie), Rayons ultraviolets, Température élevée, Virus du SRAS (), Virus du SRAS (effets des radiations), Éthanol (pharmacologie).
MESH :
- effets des radiations : Virus du SRAS.
- pharmacologie : Acétone, Anti-infectieux locaux, Antiviraux, Formaldéhyde, Glutaraldéhyde, Indicateurs et réactifs, Méthanol, Povidone iodée, Éthanol.
Pascal (Inist)
- Animaux, Cellules Vero, Inactivation virale, Rayons ultraviolets, Syndrome respiratoire aigu sévère, Povidone, Coronavirus, Iode, In vitro, Activité biologique, Antiviral, Température élevée, Virus du SRAS.
Wicri :
- topic : Iode.

English descriptors

KwdEn :
- Acetone (pharmacology), Animals, Anti-Infective Agents, Local (pharmacology), Antiviral, Antiviral Agents (pharmacology), Biological activity, Chlorocebus aethiops, Coronavirus, Ethanol (pharmacology), Formaldehyde (pharmacology), Glutaral (pharmacology), Hot Temperature, In vitro, Indicators and Reagents (pharmacology), Iodine, Methanol (pharmacology), Povidone, Povidone-Iodine (pharmacology), SARS Virus (drug effects), SARS Virus (radiation effects), Severe acute respiratory syndrome, Ultraviolet Rays, Vero Cells, Virus Inactivation.
MESH :
- chemical , pharmacology : Acetone, Anti-Infective Agents, Local, Antiviral Agents, Ethanol, Formaldehyde, Glutaral, Indicators and Reagents, Methanol, Povidone-Iodine.
- drug effects : SARS Virus.
- radiation effects : SARS Virus.
- Animals, Chlorocebus aethiops, Hot Temperature, Ultraviolet Rays, Vero Cells, Virus Inactivation.

Abstract

The efficacy of several povidone-iodine (PVP-I) products, a number of other chemical agents and various physical conditions were evaluated for their ability to inactivate the severe acute respiratory syndrome coronavirus (SARS-CoV). Treatment of SARS-CoV with PVP-I products for 2 min reduced the virus infectivity from 1.17 x 10⁶ TCID₅₀/ml to below the detectable level. The efficacy of 70% ethanol was equivalent to that of PVP-I products. Fixation of SARS-CoV-infected Vero E6 cells with a fixative including formalin, glutaraldehyde, methanol and acetone for 5 min or longer eliminated all infectivity. Heating the virus at 56°C for 60 min or longer reduced the infectivity of the virus from 2.6 x 10⁷ to undetectable levels. Irradiation with ultraviolet light at 134 μW/cm² for 15 min reduced the infectivity from 3.8 x 10⁷ to 180 TCID₅₀/ml; however, prolonged irradiation (60 min) failed to eliminate the remaining virus, leaving 18.8 TCID₅₀/ml.

Affiliations:

Japon

Le document en format XML

<record><TEI><teiHeader><fileDesc><titleStmt><title xml:lang="en" level="a">Inactivation of SARS coronavirus by means of povidone-lodine, physical conditions and chemical reagents</title>
<author><name sortKey="Kariwa, Hiroaki" sort="Kariwa, Hiroaki" uniqKey="Kariwa H" first="Hiroaki" last="Kariwa">Hiroaki Kariwa</name>
<affiliation wicri:level="1"><inist:fA14 i1="01"><s1>Laboratory of Public Health, Graduate School of Veterinary Medicine, Hokkaido University</s1>
<s2>Sapporo</s2>
<s3>JPN</s3>
<sZ>1 aut.</sZ>
<sZ>3 aut.</sZ>
</inist:fA14>
<country>Japon</country>
<wicri:noRegion>Sapporo</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="Fujii, Nobuhiro" sort="Fujii, Nobuhiro" uniqKey="Fujii N" first="Nobuhiro" last="Fujii">Nobuhiro Fujii</name>
<affiliation wicri:level="1"><inist:fA14 i1="02"><s1>Department of Microbiology, School of Medicine, Sapporo Medical University</s1>
<s2>Sapporo</s2>
<s3>JPN</s3>
<sZ>2 aut.</sZ>
</inist:fA14>
<country>Japon</country>
<wicri:noRegion>Sapporo</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="Takashima, Ikuo" sort="Takashima, Ikuo" uniqKey="Takashima I" first="Ikuo" last="Takashima">Ikuo Takashima</name>
<affiliation wicri:level="1"><inist:fA14 i1="01"><s1>Laboratory of Public Health, Graduate School of Veterinary Medicine, Hokkaido University</s1>
<s2>Sapporo</s2>
<s3>JPN</s3>
<sZ>1 aut.</sZ>
<sZ>3 aut.</sZ>
</inist:fA14>
<country>Japon</country>
<wicri:noRegion>Sapporo</wicri:noRegion>
</affiliation>
</author>
</titleStmt>
<publicationStmt><idno type="wicri:source">INIST</idno>
<idno type="inist">06-0170112</idno>
<date when="2006">2006</date>
<idno type="stanalyst">PASCAL 06-0170112 INIST</idno>
<idno type="RBID">Pascal:06-0170112</idno>
<idno type="wicri:Area/PascalFrancis/Corpus">000534</idno>
<idno type="wicri:Area/PascalFrancis/Curation">000456</idno>
<idno type="wicri:Area/PascalFrancis/Checkpoint">000462</idno>
<idno type="wicri:explorRef" wicri:stream="PascalFrancis" wicri:step="Checkpoint">000462</idno>
<idno type="wicri:doubleKey">1018-8665:2006:Kariwa H:inactivation:of:sars</idno>
<idno type="wicri:Area/Main/Merge">004663</idno>
<idno type="wicri:source">PubMed</idno>
<idno type="RBID">pubmed:16490989</idno>
<idno type="wicri:Area/PubMed/Corpus">002337</idno>
<idno type="wicri:explorRef" wicri:stream="PubMed" wicri:step="Corpus" wicri:corpus="PubMed">002337</idno>
<idno type="wicri:Area/PubMed/Curation">002337</idno>
<idno type="wicri:explorRef" wicri:stream="PubMed" wicri:step="Curation">002337</idno>
<idno type="wicri:Area/PubMed/Checkpoint">002146</idno>
<idno type="wicri:explorRef" wicri:stream="Checkpoint" wicri:step="PubMed">002146</idno>
<idno type="wicri:Area/Ncbi/Merge">001387</idno>
<idno type="wicri:Area/Ncbi/Curation">001387</idno>
<idno type="wicri:Area/Ncbi/Checkpoint">001387</idno>
<idno type="wicri:doubleKey">1018-8665:2006:Kariwa H:inactivation:of:sars</idno>
<idno type="wicri:Area/Main/Merge">004038</idno>
<idno type="wicri:Area/Main/Curation">004440</idno>
<idno type="wicri:Area/Main/Exploration">004440</idno>
</publicationStmt>
<sourceDesc><biblStruct><analytic><title xml:lang="en" level="a">Inactivation of SARS coronavirus by means of povidone-lodine, physical conditions and chemical reagents</title>
<author><name sortKey="Kariwa, Hiroaki" sort="Kariwa, Hiroaki" uniqKey="Kariwa H" first="Hiroaki" last="Kariwa">Hiroaki Kariwa</name>
<affiliation wicri:level="1"><inist:fA14 i1="01"><s1>Laboratory of Public Health, Graduate School of Veterinary Medicine, Hokkaido University</s1>
<s2>Sapporo</s2>
<s3>JPN</s3>
<sZ>1 aut.</sZ>
<sZ>3 aut.</sZ>
</inist:fA14>
<country>Japon</country>
<wicri:noRegion>Sapporo</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="Fujii, Nobuhiro" sort="Fujii, Nobuhiro" uniqKey="Fujii N" first="Nobuhiro" last="Fujii">Nobuhiro Fujii</name>
<affiliation wicri:level="1"><inist:fA14 i1="02"><s1>Department of Microbiology, School of Medicine, Sapporo Medical University</s1>
<s2>Sapporo</s2>
<s3>JPN</s3>
<sZ>2 aut.</sZ>
</inist:fA14>
<country>Japon</country>
<wicri:noRegion>Sapporo</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="Takashima, Ikuo" sort="Takashima, Ikuo" uniqKey="Takashima I" first="Ikuo" last="Takashima">Ikuo Takashima</name>
<affiliation wicri:level="1"><inist:fA14 i1="01"><s1>Laboratory of Public Health, Graduate School of Veterinary Medicine, Hokkaido University</s1>
<s2>Sapporo</s2>
<s3>JPN</s3>
<sZ>1 aut.</sZ>
<sZ>3 aut.</sZ>
</inist:fA14>
<country>Japon</country>
<wicri:noRegion>Sapporo</wicri:noRegion>
</affiliation>
</author>
</analytic>
<series><title level="j" type="main">Dermatology : (Basel)</title>
<title level="j" type="abbreviated">Dermatology : (Basel)</title>
<idno type="ISSN">1018-8665</idno>
<imprint><date when="2006">2006</date>
</imprint>
</series>
</biblStruct>
</sourceDesc>
<seriesStmt><title level="j" type="main">Dermatology : (Basel)</title>
<title level="j" type="abbreviated">Dermatology : (Basel)</title>
<idno type="ISSN">1018-8665</idno>
</seriesStmt>
</fileDesc>
<profileDesc><textClass><keywords scheme="KwdEn" xml:lang="en"><term>Acetone (pharmacology)</term>
<term>Animals</term>
<term>Anti-Infective Agents, Local (pharmacology)</term>
<term>Antiviral</term>
<term>Antiviral Agents (pharmacology)</term>
<term>Biological activity</term>
<term>Chlorocebus aethiops</term>
<term>Coronavirus</term>
<term>Ethanol (pharmacology)</term>
<term>Formaldehyde (pharmacology)</term>
<term>Glutaral (pharmacology)</term>
<term>Hot Temperature</term>
<term>In vitro</term>
<term>Indicators and Reagents (pharmacology)</term>
<term>Iodine</term>
<term>Methanol (pharmacology)</term>
<term>Povidone</term>
<term>Povidone-Iodine (pharmacology)</term>
<term>SARS Virus (drug effects)</term>
<term>SARS Virus (radiation effects)</term>
<term>Severe acute respiratory syndrome</term>
<term>Ultraviolet Rays</term>
<term>Vero Cells</term>
<term>Virus Inactivation</term>
</keywords>
<keywords scheme="KwdFr" xml:lang="fr"><term>Acétone (pharmacologie)</term>
<term>Animaux</term>
<term>Anti-infectieux locaux (pharmacologie)</term>
<term>Antiviraux (pharmacologie)</term>
<term>Cellules Vero</term>
<term>Formaldéhyde (pharmacologie)</term>
<term>Glutaraldéhyde (pharmacologie)</term>
<term>Inactivation virale</term>
<term>Indicateurs et réactifs (pharmacologie)</term>
<term>Méthanol (pharmacologie)</term>
<term>Povidone iodée (pharmacologie)</term>
<term>Rayons ultraviolets</term>
<term>Température élevée</term>
<term>Virus du SRAS ()</term>
<term>Virus du SRAS (effets des radiations)</term>
<term>Éthanol (pharmacologie)</term>
</keywords>
<keywords scheme="MESH" type="chemical" qualifier="pharmacology" xml:lang="en"><term>Acetone</term>
<term>Anti-Infective Agents, Local</term>
<term>Antiviral Agents</term>
<term>Ethanol</term>
<term>Formaldehyde</term>
<term>Glutaral</term>
<term>Indicators and Reagents</term>
<term>Methanol</term>
<term>Povidone-Iodine</term>
</keywords>
<keywords scheme="MESH" qualifier="drug effects" xml:lang="en"><term>SARS Virus</term>
</keywords>
<keywords scheme="MESH" qualifier="effets des radiations" xml:lang="fr"><term>Virus du SRAS</term>
</keywords>
<keywords scheme="MESH" qualifier="pharmacologie" xml:lang="fr"><term>Acétone</term>
<term>Anti-infectieux locaux</term>
<term>Antiviraux</term>
<term>Formaldéhyde</term>
<term>Glutaraldéhyde</term>
<term>Indicateurs et réactifs</term>
<term>Méthanol</term>
<term>Povidone iodée</term>
<term>Éthanol</term>
</keywords>
<keywords scheme="MESH" qualifier="radiation effects" xml:lang="en"><term>SARS Virus</term>
</keywords>
<keywords scheme="MESH" xml:lang="en"><term>Animals</term>
<term>Chlorocebus aethiops</term>
<term>Hot Temperature</term>
<term>Ultraviolet Rays</term>
<term>Vero Cells</term>
<term>Virus Inactivation</term>
</keywords>
<keywords scheme="Pascal" xml:lang="fr"><term>Animaux</term>
<term>Cellules Vero</term>
<term>Inactivation virale</term>
<term>Rayons ultraviolets</term>
<term>Syndrome respiratoire aigu sévère</term>
<term>Povidone</term>
<term>Coronavirus</term>
<term>Iode</term>
<term>In vitro</term>
<term>Activité biologique</term>
<term>Antiviral</term>
<term>Température élevée</term>
<term>Virus du SRAS</term>
</keywords>
<keywords scheme="Wicri" type="topic" xml:lang="fr"><term>Iode</term>
</keywords>
</textClass>
</profileDesc>
</teiHeader>
<front><div type="abstract" xml:lang="en">The efficacy of several povidone-iodine (PVP-I) products, a number of other chemical agents and various physical conditions were evaluated for their ability to inactivate the severe acute respiratory syndrome coronavirus (SARS-CoV). Treatment of SARS-CoV with PVP-I products for 2 min reduced the virus infectivity from 1.17 x 10<sup>6</sup>
 TCID<sub>50</sub>
/ml to below the detectable level. The efficacy of 70% ethanol was equivalent to that of PVP-I products. Fixation of SARS-CoV-infected Vero E6 cells with a fixative including formalin, glutaraldehyde, methanol and acetone for 5 min or longer eliminated all infectivity. Heating the virus at 56°C for 60 min or longer reduced the infectivity of the virus from 2.6 x 10<sup>7</sup>
 to undetectable levels. Irradiation with ultraviolet light at 134 μW/cm<sup>2</sup>
 for 15 min reduced the infectivity from 3.8 x 10<sup>7</sup>
 to 180 TCID<sub>50</sub>
/ml; however, prolonged irradiation (60 min) failed to eliminate the remaining virus, leaving 18.8 TCID<sub>50</sub>
/ml.</div>
</front>
</TEI>
<affiliations><list><country><li>Japon</li>
</country>
</list>
<tree><country name="Japon"><noRegion><name sortKey="Kariwa, Hiroaki" sort="Kariwa, Hiroaki" uniqKey="Kariwa H" first="Hiroaki" last="Kariwa">Hiroaki Kariwa</name>
</noRegion>
<name sortKey="Fujii, Nobuhiro" sort="Fujii, Nobuhiro" uniqKey="Fujii N" first="Nobuhiro" last="Fujii">Nobuhiro Fujii</name>
<name sortKey="Takashima, Ikuo" sort="Takashima, Ikuo" uniqKey="Takashima I" first="Ikuo" last="Takashima">Ikuo Takashima</name>
</country>
</tree>
</affiliations>
</record>

Pour manipuler ce document sous Unix (Dilib)

EXPLOR_STEP=$WICRI_ROOT/Sante/explor/SrasV1/Data/Main/Exploration

HfdSelect -h $EXPLOR_STEP/biblio.hfd -nk 004440 | SxmlIndent | more

HfdSelect -h $EXPLOR_AREA/Data/Main/Exploration/biblio.hfd -nk 004440 | SxmlIndent | more

Pour mettre un lien sur cette page dans le réseau Wicri

{{Explor lien
   |wiki=    Sante
   |area=    SrasV1
   |flux=    Main
   |étape=   Exploration
   |type=    RBID
   |clé=     Pascal:06-0170112
   |texte=   Inactivation of SARS coronavirus by means of povidone-lodine, physical conditions and chemical reagents
}}

This area was generated with Dilib version V0.6.33.
Data generation: Tue Apr 28 14:49:16 2020. Site generation: Sat Mar 27 22:06:49 2021

Serveur d'exploration SRAS

Inactivation of SARS coronavirus by means of povidone-lodine, physical conditions and chemical reagents

Inactivation of SARS coronavirus by means of povidone-lodine, physical conditions and chemical reagents

Source :

Descripteurs français

English descriptors

Abstract

Links toward previous steps (curation, corpus...)

Le document en format XML

Pour manipuler ce document sous Unix (Dilib)

Pour mettre un lien sur cette page dans le réseau Wicri

	Serveur d'exploration SRAS
	Attention, ce site est en cours de développement ! Attention, site généré par des moyens informatiques à partir de corpus bruts. Les informations ne sont donc pas validées.